RSNA 2025: GE Healthcare Showcasing Transformative Radiological Innovations

At the Radiological Society of North America’s (RSNA) 2025 Annual Meeting (Nov. 30-Dec. 4), GE HealthCare is spotlighting a plethora of solutions that are helping clinicians see more, understand more, and better care for patients.

Solving Industry Challenges

Radiology departments worldwide are facing unprecedented pressure. In the coming years, healthcare providers are expected to encounter several critical challenges, including qualified staff shortage, rising demand for imaging services, rapid technological advancements, and the urgent need to improve operational efficiency across care settings.¹ Amid these challenges, GE HealthCare is developing cloud-based and artificial intelligence (AI)-enabled innovations aimed at helping providers and clinicians turn data into actionable insights, deliver precise diagnoses and treatment plans faster than before, and help boost hospital efficiency.

At RSNA 2025, GE HealthCare is featuring more than 40 technology innovations that merge state-of-the-art imaging device technology with advanced digital, computational, and AI capabilities, and are designed to directly address these challenges—from AI-enabled imaging systems designed to reduce cognitive load and automate routine tasks to structured reporting tools that can streamline workflows and improve data consistency.

“As we shape the future of care, our commitment remains clear—to deliver transformative technologies that empower clinicians, drive efficiencies, and help improve patient outcomes across multiple care pathways,” GE HealthCare CEO Peter Arduini stated. “We start by listening to our customers, and work backwards from their challenges, then develop truly differentiated products and solutions to meet their needs today and into the future.”

GE Healthcare’s Innovation Renaissance Drivers

GE HealthCare is delivering new solutions designed to elevate patient care and enhance the clinician experience. Since 2022, the company has invested more than $3 billion in research and development, fueling a wave of innovation across equipment, radiopharmaceuticals, and cloud and AI-enabled solutions. At RSNA 2025, GE HealthCare is demonstrating new and recently announced innovations, including:

• Photonova Spectra² (510(k) pending with the U.S. Food and Drug Administration (FDA); not available for sale): The new photon counting CT (PCCT) system with advanced AI algorithms³ marks a major milestone in the company’s decades-long history in computed tomography (CT) innovation. Built on GE HealthCare’s proprietary Deep Silicon detector technology, Photonova Spectra is designed to deliver excellent spectral and spatial resolution for ultra-high-definition (UHD) imaging with wide coverage, seeking to enable fast acquisition speeds, precise visualization of anatomical structures, and enhanced material separation. This system maximizes the vast amounts of data provided, harnessing up to 50 times more data than conventional CT⁴ to enable advanced reconstruction techniques and precise outputs to support enhanced clinical decision-making and smooth workflows.
• Next-gen SIGNA MRI technology (FDA 510(k) pending; not available for sale): These technologies aim to enhance precision diagnosis for clinicians. The innovations include:
  • SIGNA Bolt⁵ is considered the most advanced high-field, clinical wide bore 3.0T MRI system that combines ultra-high gradient performance, intelligent digital RF architecture, and sustainable design to deliver precision imaging, fast workflows, and seamless clinical-to-research flexibility, all with exceptionally low energy consumption and operational costs.
  • SIGNA Sprint with Freelium⁶ aims to broaden access to sustainable and equitable MRI technology. With less than 1% helium usage compared to conventional magnets, Freelium provides effortless sustainability without compromising clinical and operational efficiency.
  • Both are powered by SIGNA One,⁷ an AI-powered workflow platform designed to improve the imaging experience by combining precision with simplicity.
• Pristina Recon DL: This solution is GE HealthCare’s advanced 3D mammography reconstruction technology—the first to combine deep learning with iterative reconstruction to provide outstanding digital breast tomosynthesis (DBT) image quality at a low patient radiation dose. Pristina Recon DL is an enhancement to GE HealthCare’s Pristina Via system. Pristina Via with Recon DL mammography system offers high clinical confidence and efficient workflows with exceptional patient experience.
• Vivid Pioneer: GE HealthCare’s most advanced and adaptive cardiovascular ultrasound platform, according to the company. With one-click optimization, AI automation tools, simplified user interface and a lighter, compact, battery supported system, Vivid Pioneer is designed for extraordinary imaging, workflow, and comfort.
• Flyrcado (flurpiridaz F 18) injection: FDA-approved PET MPI agent for adult patients with known or suspected coronary artery disease to evaluate myocardial ischemia and infarction; higher diagnostic efficacy versus SPECT, exercise-stress PET enabled by a longer half-life, and ready-to-use unit dose to support adoption. Flyrcado is expected to reach a substantial number of U.S. cardiac PET centers as adoption continues. CMS traditional pass-through status (effective April 1) supports access in HOPD settings. U.S. audiences only.
• Definium Pace Select ET: An advanced floor-mounted digital X-ray system designed to deliver high-image quality and optimize efficiency in highly demanding environments while enhancing access and affordability. The system solves many current technological challenges by automating manual, repetitive steps and helping reduce physical strain. The system leverages AI to help ensure accurate patient positioning and consistent image quality across various clinical conditions while streamlining the technologist workflow to maximize the patient experience and throughput.

GE HealthCare considers itself to be at the forefront of developing advanced AI- and cloud-enabled capabilities to help improve workflow efficiency for radiologists. Key highlights at RSNA 2025 include:

• Genesis Radiology Workspace⁸ anchored by Genesis Viewer (FDA 510(k) pending; not available for sale):⁹ Software designed to be an ultra-fast diagnostic, zero-footprint viewer – streamlining radiology workflows and aiming to enhance patient care while being fully accessible from any location. Genesis Viewer is part of the GE HealthCare’s Genesis Radiology Workspace to help streamline radiology workflows. The next-generation solution is designed to transform radiology workflows, unify the user experience, and empower radiologists with great efficiency and precision.
• One hundred FDA-authorized AI-enabled solutions: GE HealthCare leads the industry in artificial intelligence innovation, topping the FDA’s list for the most AI-enabled device authorizations of any medical device company this year. These solutions are helping to transform clinical workflows, supporting fast and precise decision-making, and expanding access to high-quality care.

“For more than 125 years, GE HealthCare has pioneered technologies that transform patient care. And while we celebrate our heritage, we remain focused on what lies ahead: a future where care is more personalized, connected, and intelligent than ever before,” GE HealthCare Imaging President Roland Rott commented. “This year at RSNA, our new innovations continue that tradition, empowering clinicians and advancing the boundaries of what’s possible in healthcare.”

A Legacy Rooted in Discovery

GE HealthCare has been shaping the future of healthcare for more than a century. From the invention of the first X-ray tube still in use in modern day imaging equipment to the current innovation renaissance, it claims to have led advances that redefine diagnostic imaging and how clinicians treat and care for patients. The company’s presence at every RSNA since its inception in 1914 reflects an enduring commitment to advance radiology and support the imaging community.

This year, GE HealthCare commemorates a series of transformative achievements that have shaped the landscape of medical imaging and patient care:

• Sixty years of mammography: Since 1965, GE HealthCare has led mammography innovation—from developing the first dedicated X-ray machine to digital, 3D, and AI-powered technologies that enable early accurate diagnoses. This ongoing commitment to women’s health empowers clinicians and aims to improve outcomes worldwide.
• Twenty-five years of PET/CT: Since introducing the world’s first commercially available PET/CT system in 2001—an innovation that would redefine diagnostic imaging and help transform patient care—GE HealthCare has expanded access and helped elevate precision medicine across care pathways. By combining functional and anatomical imaging, PET/CT has become an essential tool for clinicians, helping them detect, stage, and monitor cancer with greater accuracy and confidence.
• A legacy of industry firsts: GE HealthCare’s history is marked by groundbreaking achievements, including the development of the first full body CT scanner, the commercialization of magnetic resonance imaging (MR), the introduction of the first color pocket-size handheld ultrasound, Vscan, in 2010, and Flyrcado in 2024, a first-of-its kind PET molecular imaging agent for diagnosing and assessing coronary artery disease, a significant game-changing innovation for nuclear cardiology. Each innovation is designed to set new standards for patient care and clinical excellence.

Strategic Collaborations Driving Innovation

GE HealthCare’s commitment to advancing patient care goes beyond research and development—it’s strengthened by strategic collaborations and acquisitions that accelerate innovation. In the past year, the company has strengthened its portfolio to include:

• MIM Software, which enhances GE HealthCare’s ability to provide advanced imaging analytics, visualization, and workflow solutions
• Spectronic Medical, delivering innovations that aim to enhance radiation oncology planning
• icometrix, which further expands GE HealthCare’s leadership in AI-enabled precision imaging, facilitating neurological disorder diagnosis and monitoring of disease progression

GE HealthCare is a global healthcare solutions provider, innovating medical technology, pharmaceutical diagnostics, and integrated, cloud-first AI-enabled solutions, services, and data analytics. The company aims to make hospitals and health systems more efficient, clinicians more effective, therapies more precise, and patients healthier and happier. Serving patients and providers for more than 125 years, GE HealthCare is advancing personalized, connected and compassionate care, while simplifying the patient’s journey across care pathways. Together, its Imaging, Advanced Visualization Solutions, Patient Care Solutions and Pharmaceutical Diagnostics businesses help improve patient care from screening and diagnosis to therapy and monitoring. The company is a $19.7 billion business with approximately 53,000 colleagues.

References
¹ Elizabeth H. Dibble et al. “Workforce Shortage and Strategies for Mitigation: Results from the 2022 ACR/Radiology Business Management Association Workforce Survey.” Journal of the American College of Radiology 22, no. 5 (2025): 573–576. https://doi.org/10.1016/j.jacr.2025.01.xxx.
² Photonova Spectra is 510(k)-pending with the U.S. FDA. Not CE Marked. Not available for sale in the United States, Europe, Canada, or any other region.
³ Enhanced Boundary for PCCT is 510(k)-pending with the U.S. FDA. Not CE Marked. Not available for sale in the United States, Europe, Canada, or any other region.
⁴ When compared to Revolution Apex Elite.
⁵ SIGNA Bolt is 510(k) pending at U.S. FDA. Not CE marked. Not available for sale.
⁶ SIGNA Sprint with Freelium is a sealed configuration of SIGNA Sprint Select. SIGNA Sprint Select is 510(k) pending at U.S. FDA. Not CE marked. Not available for sale.
⁷ SIGNA One is 510(k) pending with the U.S. FDA. Not CE marked. Not available for sale.
⁸ Genesis Radiology Workspace consists of Genesis View, Enterprise Archive, Workflow Manager and App Orchestrator.
⁹ Genesis Viewer is 510(k) Pending at the U.S. FDA; not available for sale.